Maturity Melanosis Causes & Symptoms Pigmentation Treatment FMS Skin & Hair Clinics Neurocutaneous Melanosis (Neurocutaneous melanocytosis) Dermatology Advisor Smoker's melanosis Wikipedia This lovely patient was thrilled with her beautiful result after laser treatment of oral melanotic macules. I share this case to educate: laser treatment requires accurate diagnosis, an understanding of the differential Happy Wednesday! , In this video, a patients labial melanotic macule (a benign pigmented lesion) is being treated with liquid nitrogen. Labial melanotic macules are flat and asymmetrical with a Nevus of Ota: What Is It and How Is It Treated?