Mini MCAT passage: Pentose phosphate pathway and G6DP deficiency (practice) Khan Academy Glucose 6 Phosphate Dehydrogenase (G6PD) Deficiency The Medical Biochemistry Page Diabetes causes inhibition of glucose 6 phosphate dehydrogenase via activation of PKA, which contributes to oxidative stress in rat kidney cortex American Journal of Physiology Renal Physiology American Physiological Society HEMOLYTIC ANEMIA Frontiers Glucose 6 Phosphate Dehydrogenase Deficiency and Neonatal Hyperbilirubinemia: Insights on Pathophysiology, Diagnosis, and Gene Variants in Disease Heterogeneity PeerJ The research progress on the role of glucose 6 phosphate dehydrogenase in immune regulation
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glutathione g6pd G6PD Deficiency • Glucose-6-phosphate dehydrogenase deficiency • X-linked recessive disorder • Leads to low NADPH, impairing glutathione regeneration → RBCs are vulnerable to oxidative damage ⸻ Pathophysiology: In G6PD deficiency: • No